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Updated: Jan 24, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Effectiveness of Platelet-Rich Plasma in the Management of Knee Osteoarthritis in a Rural Clinic
Vincent Mogoi1, Betty Elder, Karen Hayes
1Vincent Mogoi, DNP, BSN, Wichita State University College of Health Professions, Wichita, KS. Betty Elder, PhD, RN, Wichita State University College of Health Professions, Wichita, KS. Karen Hayes, PhD, APRN, FNP-BC, ACNP-BC, Wichita State University College of Health Professions, Wichita, KS. Dawna Huhman, MSN, APRN, FNP-C, Owner/Advanced Practice Registered Nurse, Advanced Mobile Healthcare & Community Clinic, Kingman, KS.
Background:
Osteoarthritis (OA) is a degenerative disease causing decreased mobility. Use of autologous platelet-rich plasma (PRP) provides a reparative alternative in the management of OA.
Methods/Purpose:
This study assessed effectiveness of nurse practitioner-injected PRP to manage knee OA in a rural setting.
Results:
Twenty patients were followed for 1 month after PRP treatment. Knee function and pain levels were assessed using a knee function score (Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form [KOOS-PS]).
Conclusions:
Overall, the 20 patients who participated in this study experienced significant improvement in knee function scores, decreased pain, and decreased use of pain medications.
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