Related Experiment Video
Updated: Jan 23, 2026

Covalent Binding of BMP-2 on Surfaces Using a Self-assembled Monolayer Approach
Published on: August 26, 2013
Qu-anti-tative analysis of weak non-covalent inter-actions in (Z)-3-(4-chloro-phen-yl)-2-phenyl-acrylo-nitrile:
Mani Udayakumar1, Margarita Cerón2, Paulina Ceballos2
1Biomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613 401, India.
Abstract:
In the solid state, the title compound, C15H10ClN, is disordered over two orientations with a refined occupancy ratio of 0.86 (2):0.14 (2). The crystal structure is mainly stabilized by inter-molecular C-H⋯N and C-H⋯Cl hydrogen bonds, and C-H⋯π inter-actions. The mol-ecules pack in columns and adjacent columns are linked by weak C-H⋯Cl inter-actions. The PIXEL energy analysis suggests that the inter-molecular C-H⋯π inter-actions form a strong dimer in the major component. Hirshfeld analysis reveals that H⋯C, H⋯H, H⋯Cl and H⋯N contacts are the most important contributors to the crystal packing.
Related Concept Videos
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Weak Base Solutions
Covalent Bonds
Quantitative Analysis
In quantitative analysis, two key measurements are made: the sample quantity and a property proportional to the amount of the analyte (the substance being analyzed). This forms the basis of the...
Weak Acid Solutions
Covalent Bonding and Lewis Structures

![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)