Related Experiment Video For Cancer subtyping
Updated: Jan 23, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Immunohistochemistry-Enabled Precision Medicine
Zoran Gatalica1, Rebecca Feldman2, Semir Vranić3
1Caris Life Sciences, Phoenix, AZ, USA. zgatalica@carisls.com.
Abstract:
Immunohistochemistry (IHC) can be applied to diagnostic aspects of pathologic examination to provide aid in assignment of lineage and histologic type of cancer. Increasingly, however, IHC is widely used to provide prognostic and predictive (theranostic) information about the neoplastic disease. A refinement of theranostic application of IHC can be seen in the use of "genomic probing" where antibody staining results are directly correlated with an underlying genetic alteration in the tumor (somatic mutations) and/or the patient (germline constitution). All these aspects of IHC find their best use in guiding the oncologists in the optimal use of therapy for the patients.
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