Related Experiment Video
Updated: Jan 23, 2026

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
Published on: February 3, 2016
Oro-Antral Fistula Repair With Different Surgical Methods: a Retrospective Analysis of 147 Cases
Rasoul Gheisari1, Hesam Hosein Zadeh2, Saeid Tavanafar3
1Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Statement Of The Problem:
An oro-antral fistula (OAF) creates a passage for oral microbes into maxillary sinus with numerous possible complications.
Purpose:
This retrospective study evaluates the success of three different surgical techniques of OAF repair.
Materials And Method:
Records of patients that were treated for OAF repair were retrieved and reviewed. Data recorded were patients' age, gender, etiology, size, location, duration, and method of repair. According to the surgical technique used to repair the OAF, patients were divided into three groups including buccal flap, palatal flap, and buccal fat pad. All of the patients were locally anesthetized with 2% lidocaine and 1/100000 or 1/80000 epinephrine. Then the edges of the fistula were excised and fistula wall was dissected in a stitched layer by three surgical methods. The three groups were compared concerning the success or failure of surgical technique based on complete closure of OAF after three months postoperatively.
Results:
147 patients (116 males and 31 females) with adequate records were included in the study. The surgical methods used in patients were, buccal flap in 59 (40.1%), buccal fat pad in 42 (40.8%), and palatal flap in 28 (19%) individuals. Success rates of these techniques were significantly different. Buccal fat pad was the most successful flap (98.3%), followed by buccal flap (89.8%), and palatal flap (85.7%). The most common cause of OAF in this group of patients was dental extraction.
Conclusion:
Buccal fat pad flap seems to be one of the best treatments for the closure of OAF lager than 5 mm.
Related Concept Videos
Mismatch Repair
Mismatch Repair
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Overview of DNA Repair
Chemically...
Base Excision Repair
The first step of...
Nucleotide Excision Repair
Nucleotide Excision Repair
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...

