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The Man Who Saw Things on Carvedilol
Salisu A Aikoye1, Mohammad Jafferany, Vanessa Osuagwu
1Department of Psychiatry, Central Michigan University College of Medicine, Saginaw, MI, USA. 1000 Houghton Avenue, Saginaw, MI 48602, USA. aikoy1sa@cmich.edu.
Abstract:
The newer generation non selective vasodilating beta adrenergic blocking agent Carvedilol, also has an alpha 1 adrenoceptor antagonistic effect and is widely used in treating various cardiovascular diseases. It is a selective alpha and non-selective beta blocker. It's side effects are vast and not limited to any particular organ system, the neuropsychiatric adverse effects include; somnolence, nervousness, sleep disorder, aggravated depression, vivid dreams, delirium, psychosis, impaired concentration, abnormal thinking, paroniria, and emotional lability. Hallucinations are rarely reported and as far as we know the only reported couple of cases were on metoprolol and propranolol, none has been reported with Carvedilol.
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