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Updated: Jan 22, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
Published on: March 14, 2014
Decision Support Systems in Prostate Cancer Treatment: An Overview
Y van Wijk1, I Halilaj1, E van Limbergen2
1The D-Lab: Decision Support for Precision Medicine GROW - School for Oncology and Developmental Biology & MCCC, Maastricht University Medical Center, Maastricht, Netherlands.
Multifactorial decision support systems (mDSS) for prostate cancer (PCa) are well-developed for diagnosis and radiotherapy treatment. However, research gaps exist for other treatment modalities and patient decision aids, highlighting needs for personalized medicine advancement.
Area of Science:
- Urology
- Medical Informatics
- Health Services Research
Background:
- Multifactorial decision support systems (mDSS) enhance clinical decision-making by providing case-specific advice.
- Prostate cancer (PCa) management can benefit from mDSS to improve patient outcomes.
- Current literature on mDSS for PCa needs comprehensive analysis to identify existing tools and research gaps.
Purpose of the Study:
- To systematically review and analyze available mDSS for prostate cancer (PCa).
- To understand the current landscape of decision support tools in PCa care.
- To identify areas lacking mDSS development and inform future research directions.
Main Methods:
- A MEDLINE literature search was conducted in July 2018.
- Studies were categorized into diagnostic, treatment, and patient-focused mDSS.
- Manual screening excluded irrelevant studies and proposals, focusing on PCa-specific mDSS.
Main Results:
- The review identified twelve diagnostic mDSS and six treatment mDSS.
- Two patient-focused mDSS were found, alongside eight papers contributing to mDSS improvement.
- External-beam radiotherapy treatment mDSS are well-represented.
Conclusions:
- Diagnostic and external-beam radiotherapy treatment mDSS for PCa are well-documented.
- There is a notable lack of mDSS for alternative PCa treatment modalities.
- Patient decision aids for PCa are emerging but require further research and development for personalized medicine.
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