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Fascioliasis.

Santiago Mas-Coma1, Mª Adela Valero2, Mª Dolores Bargues2

  • 1Departamento de Farmacia y Tecnología Farmacéutica y Parasitología, Facultad de Farmacia, Universidad de Valencia, Valencia, Spain. S.Mas.Coma@uv.es.

Advances in Experimental Medicine and Biology
|July 13, 2019
PubMed
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Fascioliasis, a parasitic disease caused by Fasciola worms, affects both animals and humans globally. Recent findings highlight its significant impact on public health, necessitating a reclassification from a secondary zoonosis to a primary human parasitic disease.

Area of Science:

  • Veterinary Parasitology
  • Public Health
  • Infectious Diseases

Background:

  • Fascioliasis is a widespread parasitic disease caused by Fasciola hepatica and Fasciola gigantica.
  • It is a significant veterinary concern with extensive global distribution.
  • Emerging evidence indicates fascioliasis is also a substantial public health issue, affecting millions worldwide.

Purpose of the Study:

  • To review traditional and innovative aspects of fascioliasis.
  • To re-evaluate the classification of fascioliasis in human health.
  • To provide a comprehensive overview of this important parasitic disease.

Main Methods:

  • Literature review of traditional and recent studies on fascioliasis.
  • Analysis of epidemiological data on human and animal infections.
Keywords:
Fasciola giganticaFasciola hepaticaFascioliasisFood-borne trematodeTrematodeZoonoses

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  • Synthesis of information on pathogenicity and immunity.
  • Main Results:

    • Fascioliasis exhibits the widest known distribution among vector-borne parasitic diseases.
    • Estimates suggest millions are affected, particularly in Asia and Africa.
    • Increasing human cases and research on chronic disease phases support its status as a major human parasitic disease.

    Conclusions:

    • Fascioliasis is no longer considered a secondary zoonotic disease but a significant human parasitic disease.
    • Its broad distribution and public health impact warrant continued attention and research.
    • A comprehensive understanding of fascioliasis is crucial for both veterinary and human medicine.