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Related Concept Videos

Genomics02:02

Genomics

39.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Proteomics01:33

Proteomics

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
36.9K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.0K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.0K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

15.3K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
15.3K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

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The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
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Updated: Jan 22, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

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Trematode Genomics and Proteomics.

Javier Sotillo1, Mark S Pearson2, Alex Loukas2

  • 1Centre for Molecular Therapeutics, Australian Institute for Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia. javier.sotillo@jcu.edu.au.

Advances in Experimental Medicine and Biology
|July 13, 2019
PubMed
Summary
This summary is machine-generated.

Trematode infections, a neglected tropical disease, are being better understood through advances in genomics and proteomics. Research is improving our knowledge of these important parasites affecting humans and animals.

Keywords:
ControlDiagnosisDigeneaGenomicsHost–parasite relationshipsPathogenicityProteomicsTreatmentTrematode infection

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Area of Science:

  • Parasitology
  • Genomics
  • Proteomics

Background:

  • Trematode infections are widespread neglected tropical diseases with significant socioeconomic, medical, and agricultural impact.
  • These parasites infect diverse hosts and tissues, posing a global health challenge.

Purpose of the Study:

  • To review recent advances in genomics and proteomics of medically important trematodes.
  • To highlight emerging technologies and available resources for studying trematode molecular biology.

Main Methods:

  • Review of recent scientific literature focusing on trematode genomics and proteomics.
  • Analysis of technological advancements in helminth molecular studies.

Main Results:

  • Significant progress has been made in genomic and proteomic research for human-relevant trematodes (liver, blood, intestinal, lung flukes).
  • New technologies are enhancing the study of trematode biology at the molecular level.

Conclusions:

  • Genomic and proteomic data are crucial for understanding trematode biology and developing control strategies.
  • Continued investment in omic resources and technologies is vital for addressing neglected trematode infections.