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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
449
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

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Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
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Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

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Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
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Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

390
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
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Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

531
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
531
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

514
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Related Experiment Video

Updated: Jan 22, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

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Moderate Chronic Ischemic Mitral Regurgitation.

JinQiang Shen1, LiMin Xia2, Kai Song2

  • 1Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.

International Heart Journal
|July 17, 2019
PubMed
Summary
This summary is machine-generated.

Adding a mitral valve procedure (MVP) during coronary artery bypass grafting (CABG) significantly reduces residual mitral regurgitation (MR) and improves patient outcomes. This combined approach offers better results than CABG alone for moderate ischemic mitral regurgitation.

Keywords:
In-hospital adverse eventsNYHA functional statusPropensity score matchingResidual mitral regurgitation

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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
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Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery Outcomes
  • Mitral Valve Disease

Background:

  • Moderate chronic ischemic mitral regurgitation (IMR) during coronary artery bypass grafting (CABG) presents a complex clinical challenge.
  • The established benefits of concomitant mitral valve procedure (MVP) for moderate IMR during CABG remain unclear.
  • Evaluating residual mitral regurgitation (MR) and clinical outcomes is crucial for treatment optimization.

Purpose of the Study:

  • To determine the incidence of moderate or greater residual MR after CABG plus MVP for moderate chronic IMR.
  • To compare clinical outcomes between patients undergoing CABG plus MVP versus CABG alone using propensity-matched data.

Main Methods:

  • A comparative study involving two groups: CABG plus MVP (n=184) and CABG alone (n=162).
  • Propensity-matched analysis was used to compare in-hospital and follow-up outcomes.
  • Incidence of moderate or greater residual MR was assessed at 1 and 2 years postoperatively.

Main Results:

  • The rate of moderate or greater residual MR was 11.4% at 1 year and 22.9% at 2 years in the CABG plus MVP group.
  • Patients in the MVP group showed significantly lower rates of moderate or greater residual MR at all postoperative time points (P < 0.001).
  • Concomitant MVP was associated with improved NYHA functional status and no increase in in-hospital adverse events or follow-up mortality.

Conclusions:

  • Concomitant MVP during CABG for moderate chronic IMR reduces residual MR rates.
  • This combined approach improves functional status without increasing adverse events or mortality.
  • MVP should be considered for patients with moderate chronic IMR undergoing CABG.