Related Experiment Video

Updated: Jan 22, 2026

Clarifying and Imaging Candida albicans Biofilms
11:09

Clarifying and Imaging Candida albicans Biofilms

Published on: March 6, 2020

12.3K

Novel Therapies for Biofilm-Based Candida spp. Infections

Lucia Černáková1, Catilin Light2, Bahare Salehi3

  • 1Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia.

Advances in Experimental Medicine and Biology
|July 20, 2019
PubMed

Insights

Fungal infections caused by Candida species are increasing globally, especially in immunocompromised individuals. This review explores biofilm-related infections and discusses novel therapies including new drugs, natural approaches, and photodynamic therapy.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Pharmacology

Background:

  • Global rise in fungal infections, particularly Candida species.
  • Increased prevalence in immunocompromised patients and those on antimicrobial treatments.
  • Candida species exhibit high antifungal resistance and biofilm formation, complicating treatment.

Purpose of the Study:

  • To review biofilm-related infections caused by Candida species.
  • To discuss novel and emerging therapeutic strategies.
  • To provide an overview of current clinical, scientific, and academic research.

Main Methods:

  • Literature review of scientific and clinical studies.
  • Analysis of current research on Candida biofilm infections.
  • Synthesis of information on novel antifungal agents and therapies.

Main Results:

  • Candida biofilms present significant challenges in treatment due to antifungal resistance.
  • Various novel therapeutic avenues are being explored, including new antifungal drugs.
  • Natural approaches like probiotics, essential oils, plant extracts, and honey show promise.
  • Alternative methods such as photodynamic therapy are also under investigation.

Conclusions:

  • Effective management of Candida biofilm infections requires innovative therapeutic strategies.
  • A combination of conventional and novel therapies may be necessary.
  • Further research into natural products and alternative therapies is warranted.
Keywords:
BiofilmsCandida spp.DrugsEssential oilHoneyInfectionPhotodynamic therapyPlant extractPrebioticProbioticResistance

More Related Videos

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth11:06

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

Published on: April 23, 2019

8.2K
A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

3.6K

Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
1.2K
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K
Group Therapy01:26

Group Therapy

Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
375
Psychodynamic Therapy01:29

Psychodynamic Therapy

Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
525
Humanistic Therapy01:24

Humanistic Therapy

Humanistic therapies emphasize personal growth, self-understanding, and the fulfillment of human potential. Rooted in the belief that individuals inherently strive toward self-actualization, these approaches encourage clients to explore their feelings and experiences in a supportive, nonjudgmental environment. Humanistic therapies differ from psychodynamic approaches by focusing on conscious experiences, present circumstances, and the potential for self-improvement rather than past conflicts...
339
Modeling in Therapy01:26

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
388