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Updated: Jan 21, 2026

Murine Flexor Tendon Injury and Repair Surgery
Published on: September 19, 2016
Management of Chronic Tendon Injuries
Shawn F Kane1, Lucianne H Olewinski2, Kyle S Tamminga1
1University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Chronic tendon injuries, or tendinopathies, involve degenerative healing, not inflammation. Treatment focuses on activity modification, rest, pain control, and eccentric exercises for effective recovery.
Area of Science:
- Orthopedics
- Sports Medicine
- Regenerative Medicine
Background:
- Tendons possess unique biological properties enabling strength and flexibility, yet are susceptible to injury.
- Chronic tendon injuries are prevalent in athletic and occupational settings, leading to numerous medical consultations.
- The term tendinopathy accurately reflects the degenerative, rather than inflammatory, nature of pathological tendons.
Purpose of the Study:
- To provide a comprehensive overview of tendinopathy, encompassing its pathology, diagnosis, and treatment.
- To differentiate tendinopathy from tendinitis, emphasizing the underlying degenerative processes.
- To discuss current and emerging treatment modalities for chronic tendon injuries.
Main Methods:
- Diagnosis relies on patient history and physical examination.
- Radiography serves as an acceptable initial imaging modality.
- Ultrasonography and magnetic resonance imaging aid in complex or unclear cases.
Main Results:
- Treatment mainstays include activity modification, relative rest, pain management, and protection.
- Early implementation of eccentric loading exercises is crucial for rehabilitation.
- Pharmacological interventions like NSAIDs and corticosteroids, alongside cryotherapy, can manage pain and improve function, despite limited evidence of inflammation.
Conclusions:
- Tendinopathy management requires a multifaceted approach, prioritizing conservative measures and targeted rehabilitation.
- While evidence varies, interventions such as topical nitroglycerin, shock wave therapy, and PRP injections offer additional nonsurgical options.
- Careful consideration of corticosteroid injections is necessary due to the risk of tendon rupture.
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