Related Experiment Video
Updated: Jan 21, 2026

Extracting DNA from the Gut Microbes of the Termite Zootermopsis Angusticollis and Visualizing Gut Microbes
Published on: May 28, 2007
Mood and Microbes: Gut to Brain Communication in Depression
John R Kelly1, Veronica O' Keane1, John F Cryan2
1Department of Psychiatry, Trinity College Dublin and Tallaght Hospital, Trinity Centre for Health Sciences, Tallaght University Hospital, Dublin 24, Ireland.
Abstract:
The gut microbiota, acting via the gut-brain axis, modulates key neurobiological systems that are dysregulated in stress-related disorders. Preclinical studies show that the gut microbiota exerts an influence over neuroimmune and neuroendocrine signaling pathways, in addition to epigenetic modification, neurogenesis, and neurotransmission. In humans, preliminary evidence suggests that the gut microbiota profile is altered in depression. The full impact of microbiota-based treatments, at different neurodevelopmental time points, has yet to be fully explored. The integration of the gut microbiota, as a mediator, in the complex trajectory of depression, may enhance the possibility of personalized precision psychiatry.
More Related Videos
07:29Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
Published on: December 29, 2023
10:24Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
Published on: July 4, 2018
Related Concept Videos
Neurons as Communicators of the Brain
Cell Body
The cell body, also known...
Communication
Communication
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Traits, Mood, and Subjective Wellbeing
Neuroticism and...