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Strategy for Contiguous Tetramination of Cyclohexanones with o-Phenylenediamines with Elemental Sulfur and DMSO
Thanh Binh Nguyen1, Le Anh Nguyen2,3, Pascal Retailleau1
1Institut de Chimie des Substances Naturelles , CNRS UPR 2301, Université Paris-Sud, Université Paris-Saclay, 1 avenue de la Terrasse , 91198 Gif-sur-Yvette , France.
Abstract:
The S8/DMSO combination was found to be an excellent oxidizing agent for ipso,α,β,γ-tetramination of cyclohexanones with two molecules of o-phenylenediamines in the presence of TFA as a catalyst. The strategy could be applied to pyrido cyclohexanes as a direct method to extend the fused heteroaromatic system.
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