Related Experiment Video
Updated: Jan 20, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
Multimodal Analysis of Hyperautofluorescent Ring Size in Retinitis Pigmentosa
Background And Objective:
To determine if a correlation exists between hyperautofluorescent ring size with visual acuity (VA), foveal avascular zone (FAZ) size, and retinal capillary perfusion density (CPD) in retinitis pigmentosa (RP).
Patients And Methods:
Eighteen eyes from nine patients with RP were imaged using fundus autofluorescence (AF) to identify autofluorescence defects, and hyperautofluorescent ring size was measured with an image-processing program. Spectral-domain optical coherence tomography angiography was used to measure FAZ area and calculate parafoveal CPD in the superficial capillary plexus (SCP) and the deep capillary plexus (DCP) using both a 3 mm × 3 mm and 6 mm × 6 mm strategy.
Results:
The area of hyperautofluorescence was not strongly correlated with SCP perfusion density (P = .74), DCP perfusion density (P = .25), FAZ area (P = .14), or VA (P = .33).
Conclusion:
The area of the hyperautofluorescent ring does not correlate with VA, retinal CPD, or FAZ area. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:492-496.].
Related Concept Videos
Cell Size
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
Brick Sizes
Modular bricks are the most common type and are sized to include the mortar joint, which is essential for...
Genome Size and the Evolution of New Genes
Genome Size and the Evolution of New Genes
Maximum Size of Aggregate
Sample Size Calculation
The sample size for the given experiment or sampling effort is fundamental to any study design. Sample size decides the number of...

