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Inflammation01:38

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Jan 20, 2026

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation
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Inflammation and cancer.

Nitin Singh1, Deepak Baby2, Jagadish Prasad Rajguru3

  • 1Department of Pedodontics and Preventive Dentistry, Chandra Dental College and Hospital, Safedabad, Barabanki, Uttar Pradesh, India.

Annals of African Medicine
|August 17, 2019
PubMed
Summary
This summary is machine-generated.

Inflammation plays a key role in cancer development and progression. Targeting inflammation offers a promising strategy for both cancer prevention and therapy due to the stability of involved cells against drug resistance.

Keywords:
Cancercellsinflammation

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Area of Science:

  • Oncology
  • Immunology
  • Cancer Research

Background:

  • Inflammation is intrinsically linked to cancer development and progression.
  • Genetically stable cells driving cancer-associated inflammation are less prone to drug resistance.
  • Tumor-extrinsic factors (infections, obesity, smoking) and intrinsic factors (mutations) can both promote inflammation and cancer.

Purpose of the Study:

  • To review the multifaceted relationship between inflammation and cancer.
  • To highlight inflammation as a potential therapeutic and preventative target in oncology.

Main Methods:

  • Literature review and synthesis of existing research on inflammation and cancer.
  • Analysis of mechanisms by which extrinsic and intrinsic inflammation influence cancer progression.
  • Examination of the role of inflammation in creating an immunosuppressive tumor microenvironment.

Main Results:

  • Both external factors and cancer-intrinsic processes can elicit inflammation that promotes tumor growth.
  • Inflammation, whether extrinsic or intrinsic, can lead to immunosuppression, facilitating tumor development.
  • The stability of inflammatory cells suggests a viable target for anti-cancer strategies.

Conclusions:

  • Inflammation is a critical component in the development and progression of cancer.
  • Targeting cancer-associated inflammation presents a viable strategy for cancer prevention and treatment.
  • Understanding the dual role of inflammation (extrinsic and intrinsic) is key to developing novel therapeutic approaches.