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Precision medicine in diabetes.

Sanjay Kalra1, Sandeep Chaudhary2

  • 1Department of Endocrinology, Bharti Hospital, Karnal, India.

JPMA. the Journal of the Pakistan Medical Association
|September 13, 2019
PubMed
Summary

Precision medicine offers tailored approaches for diabetes care, improving diagnosis, pharmacotherapy, and complication management. This review simplifies the concept for physicians, enhancing patient outcomes through personalized treatment strategies.

Keywords:
Genes, metformin, monogenic diabetes, repaglinide, sulfonylureas, incretins.

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Area of Science:

  • Endocrinology and Metabolism
  • Genomics and Personalized Medicine

Background:

  • Precision medicine is revolutionizing healthcare by tailoring treatments to individual variability.
  • Diabetes mellitus presents a complex challenge due to its heterogeneous nature and diverse patient population.

Purpose of the Study:

  • To elucidate the evolving concept of precision medicine.
  • To detail the application of precision medicine in diabetes mellitus management.
  • To provide a clear understanding for practicing physicians.

Main Methods:

  • This review synthesizes current literature on precision medicine.
  • It focuses on three key areas within diabetes care: diagnosis, pharmacotherapy, and complication management.

Main Results:

  • Precision medicine enables more accurate diagnosis of diabetes subtypes.
  • It guides the selection of optimal glucose-lowering pharmacotherapy based on individual patient profiles.
  • Personalized strategies enhance the management of diabetes-related complications.

Conclusions:

  • Precision medicine holds significant potential to transform diabetes care.
  • Adoption of precision medicine principles can lead to improved patient outcomes and more effective disease management.
  • This review serves as a guide for physicians integrating precision medicine into diabetes practice.