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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds04:58

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

This article provides a detailed and visual description of a methodology for collecting and measuring biochemical inflammatory and nociceptive mediators at the surgical wound site following cesarean delivery. This human bioassay has been used to determine correlations between wound and serum cytokine concentrations and drug-mediated changes in wound cytokines, chemokines and...
12.4K
Demonstration of the Rat Ischemic Skin Wound Model08:35

Demonstration of the Rat Ischemic Skin Wound Model

The rat, due to its size, availability, and rather docile behavior, has been utilized as a research model for many years. The goal of this protocol is to utilize the rat as an ischemic skin wound healing model to provide valuable insight into the pathophysiology of chronic...
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Swine Model of Biofilm Infection and Invisible Wounds07:16

Swine Model of Biofilm Infection and Invisible Wounds

Chronic wounds that are resistant to antibiotics are a major threat to the healthcare system. Biofilm infections are stubborn and hostile and can cause deficient functional wound closure. We report a clinically relevant swine model of biofilm-infected full-thickness chronic wounds. This model is powerful for mechanistic studies as well as for testing...
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Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.09:06

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Here, two murine wound healing models are described, one designed to assess cellular and cytokine wound healing responses and the other to quantify the rate of wound closure. These methods can be used with complex disease models such as diabetes to determine mechanisms of various aspects of poor wound...
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Methods for Skin Wounding and Assays for Wound Responses in C. elegans09:06

Methods for Skin Wounding and Assays for Wound Responses in C. elegans

The adult C. elegans skin is a tractable model for studies of epithelial wound responses, including wound closure, scar formation, and innate immunity.
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Murine Model of Wound Healing05:39

Murine Model of Wound Healing

A murine model of cutaneous wound healing that can be used to assess therapeutic compounds in physiological and pathophysiological...
67.2K