Related Experiment Video
Updated: Jan 19, 2026
Appendicitis-I: Introduction
Volume of Irrigation Does Not Affect Rate of Abscess in Perforated Appendicitis
Kate B Savoie1, Rita D Shelby1, Michael W Dykes2
1Department of Surgery, Nationwide Children's Hospital, Columbus, Ohio.
Abstract:
Although previous studies have evaluated whether use of irrigation decreases postoperative intraabdominal abscess (PO-IAA) formation, these studies treated irrigation as a dichotomous variable and concluded that no irrigation resulted in a decreased incidence of PO-IAA formation. However, a recent study found decreased incidence with small aliquots to a total volume of 6 L. We hypothesized that higher volumes of irrigation would result in a lower incidence of PO-IAA. A postoperative template was developed as a quality improvement initiative and included descriptors for complex appendicitis and volume of irrigation. Data were prospectively collected from February 2016 to December 2018. Patients with complex appendicitis (fibropurulent exudate, extraluminal fecalith, well-formed abscess, visible hole in the appendix) were identified and analyzed by using standard statistical analysis. Volume of irrigation was categorized for analysis. Two thousand three hundred six appendicitis patients were identified; 408 had complex appendicitis (17.7%). Three hundred eighty-four patients with complex appendicitis had documented irrigation volumes. The overall incidence of PO-IAA was 13.8%. Irrigation was commonly used (92.7%). The median amount of irrigation was 1000 mL (500 mL, 2500 mL), but it ranged from none to 9000 mL. There was no overall difference in the volume of irrigation used between those who developed a PO-IAA and those who did not (P = .34). No specific intraoperative finding was associated with the development of PO-IAA. Increasing volume of irrigation did not lower PO-IAA incidence (P = .24). The volume of irrigation did not appear to affect the rate of PO-IAA formation. The use of irrigation should be left to the discretion of the operating surgeon.
Insights
This study found that increasing the volume of intraabdominal irrigation during appendectomy did not reduce the incidence of postoperative intraabdominal abscess (PO-IAA). The decision to use irrigation should remain with the operating surgeon.
Area of Science:
- Surgical Innovation
- Infectious Disease Management
- Clinical Outcomes Research
Background:
- Previous research on intraabdominal irrigation for appendicitis yielded conflicting results regarding postoperative intraabdominal abscess (PO-IAA) formation.
- Studies often treated irrigation as a binary variable, overlooking the impact of varying irrigation volumes.
- Recent findings suggested potential benefits of large-volume irrigation, prompting further investigation.
Purpose of the Study:
- To investigate the hypothesis that higher volumes of intraabdominal irrigation decrease the incidence of PO-IAA in complex appendicitis.
- To analyze the relationship between irrigation volume and PO-IAA rates in a prospectively collected cohort.
Main Methods:
- A quality improvement initiative prospectively collected data from February 2016 to December 2018.
- Patients with complex appendicitis were identified based on specific intraoperative findings.
- Irrigation volumes were documented and analyzed statistically, with volumes categorized for comparison.
Main Results:
- Of 2,306 appendicitis patients, 408 had complex appendicitis, with 384 having documented irrigation volumes.
- The overall PO-IAA incidence was 13.8%, with irrigation used in 92.7% of cases.
- No significant difference in PO-IAA incidence was observed based on irrigation volume (P=.34), and increasing volume did not lower PO-IAA rates (P=.24).
Conclusions:
- The volume of intraabdominal irrigation does not appear to influence the rate of PO-IAA formation in complex appendicitis.
- The decision regarding the use of intraabdominal irrigation should be at the discretion of the operating surgeon.
- Further research may explore other factors influencing PO-IAA development in complex appendicitis.
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