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Time-Based Prospective Memory Is Associated with Functional Performance in Persons with MS.

Erica Weber1,2, Nancy D Chiaravalloti1,2, John DeLuca1,2,3

  • 1Kessler Foundation, East Hanover, NJ 07936, USA.

Journal of the International Neuropsychological Society : JINS
|September 24, 2019
PubMed
Summary
This summary is machine-generated.

Individuals with multiple sclerosis (MS) experience difficulties with time-based prospective memory (PM), impacting daily functioning. This study found time-based PM deficits in MS are linked to executive functions and real-world activities.

Keywords:
Activities of daily livingMemory (episodic)Multiple sclerosisNeurocognitive disordersTime factors

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Clinical Psychology

Background:

  • Prospective memory (PM) failures are common in multiple sclerosis (MS) and affect daily life.
  • The relationship between specific types of PM deficits and everyday functioning in MS is not well understood.

Purpose of the Study:

  • To compare time-based PM (Time-PM) and event-based PM (Event-PM) in individuals with MS and healthy controls (HCs).
  • To investigate the cognitive correlates of PM in MS.
  • To examine the association between PM performance and everyday functioning in MS.

Main Methods:

  • A between-subjects design comparing 30 adults with MS and 30 HCs.
  • Utilized the Memory for Intentions Screening Test (MIST) for PM assessment.
  • Employed the Actual Reality™ (AR) for everyday functioning and a cognitive test battery.

Main Results:

  • The MS group showed significantly poorer performance on Time-PM compared to HCs, but not on Event-PM.
  • Both Time-PM and Event-PM correlated with retrospective memory, while Time-PM also correlated with executive functions.
  • Everyday functioning (AR) was significantly correlated with Time-PM, but not Event-PM.

Conclusions:

  • Executive functions play a crucial role in Time-PM performance in MS.
  • The findings support the ecological validity of the MIST for assessing PM in MS populations.
  • Time-based PM deficits are linked to impaired everyday functioning in individuals with MS.