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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Related Experiment Video

Updated: Jan 5, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Management Of Glaucoma In Developing Countries: Challenges And Opportunities For Improvement.

Maria Fernanda Delgado1, Ahmed Mostafa Abdelrahman2, Malika Terahi3

  • 1Private Practice and Sociedad de Cirugía Ocular, Bogotá, Colombia.

Clinicoeconomics and Outcomes Research : CEOR
|October 22, 2019
PubMed
Summary

Glaucoma, a leading cause of blindness, poses significant economic and humanistic burdens, especially in aging developing nations. This study explores management challenges and cost-effective strategies to improve care and prevent vision loss.

Keywords:
accesscostdevelopinghealthcare systemocular surface diseasepreservative-freequality

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Area of Science:

  • Ophthalmology
  • Public Health
  • Health Economics

Background:

  • Glaucoma is a primary cause of irreversible blindness globally.
  • The disease presents substantial clinical, economic, and humanistic burdens on patients, caregivers, and society.
  • Aging populations in developing countries exacerbate the impact of glaucoma.

Purpose of the Study:

  • To examine the multifaceted burdens of glaucoma, with a specific emphasis on developing countries.
  • To discuss challenges in providing optimal glaucoma management under budget constraints.
  • To propose strategies for improving healthcare systems, leveraging technology, and balancing cost with quality of care.

Main Methods:

  • Review of existing literature on glaucoma's impact and management.
  • Analysis of economic and humanistic burdens in developing countries.
  • Exploration of healthcare system improvements and technological integration.

Main Results:

  • Glaucoma's burden is significant and growing, particularly in aging developing nations.
  • Effective glaucoma management faces challenges related to cost and healthcare infrastructure.
  • Potential exists for cost savings through optimized care strategies.

Conclusions:

  • Addressing glaucoma requires innovative approaches to healthcare delivery and resource allocation.
  • Balancing cost and quality is crucial for sustainable glaucoma management.
  • Policy considerations should focus on long-term savings and WHO Vision goals.