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Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
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Objective Evaluation of Proliferative Diabetic Retinopathy Using OCT.
Roy Schwartz1, Hagar Khalid2, Sobha Sivaprasad1
1NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.
Ophthalmology. Retina
|November 12, 2019
Summary
Structural OCT excels at detecting new neovascularization in proliferative diabetic retinopathy (PDR). B-scan OCT angiography (OCTA) is superior for monitoring disease regression or reactivation, aiding in PDR management.
Area of Science:
- Ophthalmology
- Medical Imaging
- Diabetology
Background:
- Proliferative diabetic retinopathy (PDR) is a leading cause of vision loss.
- Objective diagnosis and monitoring are crucial for effective PDR management.
- Traditional methods may have limitations in detecting subtle disease changes.
Purpose of the Study:
- To evaluate the routine use of Optical Coherence Tomography (OCT) and OCT angiography (OCTA) for diagnosing and monitoring PDR.
- To compare the detection rates of neovascularization using different imaging modalities.
Main Methods:
- Retrospective analysis of 47 eyes from 35 patients with PDR.
- Standardized PDR imaging protocol including structural OCT and OCTA.
- Comparison of detection rates for neovascularization (NV) and tractional retinal detachment (TRD) with biomicroscopy, color photography, and OCT/OCTA.
Main Results:
- Structural OCT achieved 100% detection of new neovascularization of the disc (NVD) and elsewhere (NVE).
- B-scan OCTA demonstrated 100% detection of NV regression or reactivation, outperforming structural OCT.
- OCT identified fovea-threatening tractional retinal detachment in 7 of 10 affected eyes.
Conclusions:
- Multimodal imaging, including OCT and OCTA, is valuable for daily PDR management.
- Structural OCT is optimal for detecting NV, while B-scan OCTA shows promise for monitoring treatment response.
- Objective monitoring with OCT/OCTA can improve patient outcomes in PDR.
