Related Experiment Video

Updated: Jan 4, 2026

Author Spotlight: Advancing Personalized Medicine in Ovarian Cancer
08:26

Author Spotlight: Advancing Personalized Medicine in Ovarian Cancer

Published on: February 23, 2024

2.6K

Nutrition, Cancer and Personalized Medicine

Jóse Ali Flores-Pérez1, Fabiola de la Rosa Oliva2, Yacab Argenes3

  • 1Laboratorio de Oncogenomica, Nanopharmacia Diagnostica, Mexico City, Mexico. jose.ali@nanopharmacia.com.

Advances in Experimental Medicine and Biology
|November 13, 2019
PubMed

Insights

Diet significantly impacts cancer treatment by interacting with therapies and affecting patient nutrition. This review explores metabolic disorders and phytochemicals like resveratrol and curcumin in cancer care.

Area of Science:

  • Oncology
  • Nutritional Science
  • Biochemistry

Background:

  • Cancer involves deregulated signaling pathways affecting cell proliferation, angiogenesis, metastasis, and apoptosis.
  • Diet is crucial in oncological patient care, with potential interactions between food and cancer therapies.
  • Cancer treatments can cause malnutrition by impacting taste, appetite, and nutrient absorption.

Purpose of the Study:

  • To review the role of metabolic disorders in cancer.
  • To examine the mechanisms of action of key phytochemicals in cancer treatment.
  • To highlight the importance of diet in managing cancer and its therapies.

Main Methods:

  • Literature review of cancer signaling pathways and metabolic disorders.
  • Analysis of the impact of diet on cancer therapy efficacy.
  • Review of phytochemical mechanisms (resveratrol, EGCG, curcumin, lycopene).

Main Results:

  • Dietary components can influence cancer progression and treatment outcomes.
  • Phytochemicals exhibit potential anti-cancer properties through various biological mechanisms.
  • Malnutrition is a common complication of cancer therapy, necessitating nutritional support.

Conclusions:

  • Integrating nutritional strategies is essential for optimizing cancer patient care.
  • Understanding phytochemical actions can inform dietary recommendations for cancer patients.
  • Further research into diet-cancer therapy interactions is warranted.
Keywords:
BiomarkerCancerCurcuminDietEGCGLycopeneNutritionPersonalized therapyPrecision therapyResveraterolTargeted therapy

More Related Videos

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

17.0K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.2K

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.8K
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
53.3K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
7.6K
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.7K
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
907