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Quantification of Hypopigmentation Activity In Vitro
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Light and electron microscopy of chlorpromazine-induced hyperpigmentation

Talita Calheiros1, Hiram L de Almeida2, Valéria M Jorge1

  • 1Post-Graduation Program in Health, Catholic University of Pelotas, Pelotas, Brazil.

Journal of Cutaneous Pathology
|November 13, 2019
PubMed
Summary

Chlorpromazine can cause blue-gray skin discoloration due to pigment deposits in the dermis. This study investigated the complex mechanism behind this drug-induced hyperpigmentation.

Keywords:
chlorpromazinehyperpigmentationscanning electron microscopytransmission electron microscopy

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