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Gestational Trophoblastic Disease-induced Thyroid Storm.

Carly Blick1, Kraftin E Schreyer1

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Gestational trophoblastic diseases (GTD) can cause hyperthyroidism, a rare but dangerous thyroid storm. This case highlights GTD-induced thyroid storm presenting with vaginal bleeding, fever, and tachycardia.

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Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Critical Care Medicine

Background:

  • Gestational trophoblastic diseases (GTD) affect 121 in 100,000 pregnancies in the US.
  • Hyperthyroidism is a known complication of GTD.
  • GTD-induced thyroid storm is a rare, life-threatening condition.

Observation:

  • This report details a case of molar pregnancy-induced thyroid storm.
  • The patient presented with vaginal bleeding, fever, and tachycardia.
  • These symptoms are critical indicators of a potential thyroid storm.

Findings:

  • The case illustrates a severe presentation of GTD complications.
  • Thyroid storm in the context of molar pregnancy is a critical medical emergency.
  • Early recognition of symptoms like vaginal bleeding, fever, and tachycardia is vital.

Implications:

  • This case underscores the importance of considering thyroid storm in patients with GTD presenting with specific symptoms.
  • Prompt diagnosis and management, including mole evacuation once stable, are crucial for patient survival.
  • Increased awareness among healthcare providers can improve outcomes for this rare but severe complication.