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Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
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Individualized Treatment Strategy for Depressive Disorder
1Clinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. doctorcj2010@gmail.com.
Advances in Experimental Medicine and Biology
|December 1, 2019
Summary
Precision psychiatry aims to improve diagnosis and treatment for depressive disorders using biomarkers and advanced technologies. This approach seeks to achieve full symptom remission and functional recovery for patients, preventing recurrence.
Area of Science:
- Psychiatry
- Genomics
- Computational Biology
Background:
- Depressive disorders often lack full symptom remission and functional recovery with standard treatments.
- Individualized treatment in psychiatry aims to enhance diagnostic precision, prognosis, and therapeutic selection.
- Current treatment limitations necessitate novel approaches for better patient outcomes.
Purpose of the Study:
- To review the advancements in precise treatment for depressive disorders.
- To highlight the role of biomarkers and new technologies in personalized psychiatric care.
- To explore the potential of precision medicine for achieving complete remission and functional recovery.
Main Methods:
- Review of current literature on precision psychiatry and depressive disorders.
- Exploration of diverse techniques including genomics, epigenomics, neural circuit analysis, and artificial intelligence.
- Focus on the identification and application of biomarkers for treatment selection.
Main Results:
- Precision psychiatry utilizes omics, neural circuit, and AI to identify potential biomarkers.
- Biomarker-based treatment, guided by precision psychiatry, offers improved prognosis for patients with similar endophenotypes.
- Individualized treatment choices are crucial for optimizing intervention strategies.
Conclusions:
- Precision medicine and individualized treatment are advancing the care of depressive disorders.
- Biomarkers and emerging technologies are key to achieving complete remission and functional recovery.
- These advancements promise better lives for individuals suffering from depressive disorders.
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