Related Experiment Video
Updated: Jan 2, 2026

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
Published on: June 6, 2025
Comparative Evaluation of 15 Laser and Perfluorodecalin Combinations for Tattoo Removal
Curtis L Hardy1, Ramya Kollipara2, Elika Hoss2
1Naval Medical Center San Diego, San Diego, California, 92134.
Background And Objectives:
We present a case of laser tattoo removal treated with 15 different combinations using picosecond 1064 nm, picosecond 755 nm, nanosecond 755 nm, and a fractionated CO2 laser, both with and without a perfluorodecalin (PFD) patch to ascertain the most effective approach. STUDY DESIGN/MATERIALS AND METHODS: A single lower extremity black tattoo was divided into 15 treatment sections allowing for testing of various laser and PFD combinations. Sectioned treatment was conducted until a treatment superiority was noted.
Results:
After two sessions using sectioned combination treatments with a 4-week interval clinically significant results were produced.
Conclusions:
The combination of picosecond 1064 nm, picosecond 755 nm, and a fractionated CO2 laser without the PFD patch showed superior clinical improvement over the other combinations. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.

