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Updated: Jan 2, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

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DaT Scan "Abnormality" in Hyperglycemic-Hemichorea.

Nicholas Doher¹, Harsh V Gupta¹

¹Department of Neurology, Kansas University Medical Center, Kansas City, KS, USA.

Tremor and Other Hyperkinetic Movements (New York, N.Y.)

|December 12, 2019

Summary

This summary is machine-generated.

Hyperglycemic-hemichorea can alter brain MRI findings. A DaT scan in this context may show reduced uptake, emphasizing the need for careful clinical correlation to avoid misinterpretation.

Keywords:

DaT scan basal ganglia hemiballism hemichorea hyperglycemia

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Area of Science:

Neurology
Radiology
Nuclear Medicine

Background:

Hyperglycemic-hemichorea is a recognized neurological condition.
It is associated with characteristic signal changes observed on brain Magnetic Resonance Imaging (MRI).

Observation:

A case study involved a 57-year-old female presenting with hemichorea secondary to hyperglycemia.
Brain MRI revealed increased T1 signal intensity in the bilateral lenticular nuclei.
DaT scan demonstrated reduced bilateral uptake.

Findings:

The DaT scan findings in this hyperglycemic-hemichorea case showed reduced uptake bilaterally.
This contrasts with typical DaT scan patterns in other movement disorders.

Implications:

This case underscores the critical importance of integrating clinical context with neuroimaging results.
Abnormalities on brain MRI in hyperglycemic-hemichorea can potentially lead to false-positive interpretations of DaT scans.
Accurate diagnosis requires correlating DaT scan results with clinical presentation and other imaging modalities.