The Use of Probiotic with ORS and ORS Only in Children with Acute Diarrhea

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Rida Ali1

  • 1Department of Paediatrics, Bahria Medical University, Karachi, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|December 17, 2019
PubMed

Insights

Combination therapy with probiotics and oral rehydration solution (ORS) significantly reduced stool frequency in children with acute diarrhea compared to ORS alone. This probiotic intervention offers a more effective treatment for reducing diarrhea symptoms in pediatric patients.

Area of Science:

  • Pediatric Medicine
  • Gastroenterology
  • Microbiology

Background:

  • Acute diarrhea is a common pediatric illness, leading to significant morbidity.
  • Oral rehydration solution (ORS) is a standard treatment, but reducing stool frequency remains a challenge.

Purpose of the Study:

  • To compare the efficacy of probiotic (Lactobacillus rhamnosus) combined with ORS versus ORS alone in reducing stool frequency in children with acute diarrhea.

Main Methods:

  • A randomized controlled trial involving 80 children with acute watery diarrhea.
  • Children were divided into two groups: one receiving probiotic with ORS, the other receiving ORS only.
  • Monitoring included stool frequency, age, gender, weight, and dehydration status over 5 days.

Main Results:

  • The mean number of stools per day was significantly lower in the group treated with probiotic (Lactobacillus rhamnosus) plus ORS compared to the ORS-only group (3.25 ±1.13 vs. 4.13 ±0.79; p<0.001).
  • The study included children with an average age of 24.3 ±18.65 months, with 58.8% males and 41.3% females.

Conclusions:

  • Combination therapy with Lactobacillus rhamnosus and ORS is significantly more effective than ORS alone in reducing stool frequency in acute diarrhea.
  • Probiotics demonstrate a beneficial role in managing pediatric acute diarrhea by decreasing stool output.
Abstract

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