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Related Concept Videos

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
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Other Disorders of Digestive System01:30

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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

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Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
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Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

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The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
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Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

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Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
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What is Monogastric Digestion?01:50

What is Monogastric Digestion?

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury
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[Gastric damage in systemic sarcoidosis].

A A Perminova1, I V Antonova1

  • 1V.A. Almazov National Medical Research Center, Ministry of Health of Russia, Saint-Petersburg, Russia.

Arkhiv Patologii
|December 19, 2019
PubMed
Summary

Sarcoidosis, a multisystem disease, can affect the gastrointestinal tract, particularly the stomach. This study details pathological changes in gastric sarcoidosis, aiding diagnosis and differential diagnosis.

Keywords:
gastric sarcoidosisgranulomatous gastritissarcoidosis

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Area of Science:

  • Gastroenterology
  • Pathology
  • Immunology

Background:

  • Sarcoidosis is a multisystem inflammatory disease of unknown cause.
  • Granulomas without caseous necrosis characterize sarcoidosis.
  • Gastrointestinal involvement, though rare, can occur in sarcoidosis.

Purpose of the Study:

  • To describe pathological changes in gastric sarcoidosis.
  • To aid in the diagnosis and differential diagnosis of gastric sarcoidosis.
  • To compare findings with existing literature.

Main Methods:

  • Detailed examination of gastric wall tissue specimens.
  • Comparative analysis of pathological findings with literature data.

Main Results:

  • Detailed description of granulomatous inflammation in the gastric wall.
  • Identification of characteristic pathological features of gastric sarcoidosis.

Conclusions:

  • Gastric sarcoidosis presents diagnostic challenges due to its rarity.
  • Understanding pathological changes is crucial for accurate diagnosis.
  • This study provides valuable insights for clinicians and pathologists.