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Updated: Jan 1, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
Emerging Drug Therapies for Inherited Retinal Dystrophies
Husvinee Sundaramurthi1,2,3,4,5, Ailís Moran6,7, Andrea Cerquone Perpetuini6,7
1UCD Conway Institute, University College Dublin,, Dublin, Ireland. husvinee.sundaramurthi@ucd.ie.
Abstract:
Worldwide, 1 in 2000 people suffer from inherited retinal dystrophies (IRD). Individuals with IRD typically present with progressive vision loss that ultimately results in blindness. Unfortunately, effective treatment options are not widely available due to the genetic and clinical heterogeneity of these diseases. There are multiple gene, cell, and drug-based therapies in various phases of clinical trials for IRD. This mini-review documents current progress made in drug-based clinical trials for treating IRD.

