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Glycosaminoglycans

Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...

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Updated: Dec 31, 2025

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

Dynamic plant-derived polysaccharide-based hydrogels.

Pejman Heidarian¹, Abbas Z Kouzani¹, Akif Kaynak¹

¹School of Engineering, Deakin University, Geelong, Victoria 3216, Australia.

Carbohydrate Polymers

|January 1, 2020

Summary

This summary is machine-generated.

Plant-derived polysaccharides create advanced hydrogels with self-healing abilities. This review explores dynamic hydrogel network designs for improved self-healing and self-recovery in tissue engineering and beyond.

Keywords:

Dynamic hydrogels Dynamic linkages Plant-derived polysaccharides Self-healing Self-recovery

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Last Updated: Dec 31, 2025

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Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Area of Science:

Materials Science
Biomaterials Engineering
Polymer Chemistry

Background:

Plant-derived polysaccharides offer excellent biocompatibility and tunability for hydrogel fabrication.
Nanocellulose, a plant polysaccharide, shows promise for tissue engineering hydrogels due to superior mechanical and biological characteristics.
Conventional hydrogels lack self-healing capabilities, limiting their use in dynamic applications.

Purpose of the Study:

To review recent advancements in dynamic hydrogels synthesized from plant-derived polysaccharides.
To elucidate the relationship between hydrogel network design and dynamic properties like self-healing and self-recovery.
To discuss the applications and future prospects of these dynamic hydrogels.

Main Methods:

Literature review of research on plant-derived polysaccharides for dynamic hydrogel fabrication.
Analysis of network designs incorporating reversible crosslinks to achieve self-healing properties.
Exploration of structure-property relationships governing self-healing and self-recovery mechanisms.

Main Results:

Dynamic hydrogels from plant polysaccharides can be engineered with significant self-healing and self-recovery functionalities.
Network design, particularly the choice of reversible crosslinks, is crucial for achieving desired dynamic properties.
These hydrogels demonstrate potential in diverse fields including tissue engineering, sensors, and bioelectronics.

Conclusions:

Dynamic hydrogels derived from plant polysaccharides represent a significant advancement over conventional materials.
Tailoring network architecture is key to unlocking robust self-healing and self-recovery for advanced applications.
Further research into challenges and prospects will drive innovation in this field.