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Risk Factors for Frailty and Cardiovascular Diseases: Are They the Same?

Karolina Piotrowicz1, Jerzy Gąsowski2

  • 1Department of Internal Medicine and Gerontology, Medical College, Jagiellonian University, Kraków, Poland.

Advances in Experimental Medicine and Biology
|January 3, 2020
PubMed

Insights

As populations age, cardiovascular disease and frailty syndrome increase. These conditions share risk factors like hypertension and inflammation, worsening outcomes for older adults.

Area of Science:

  • Gerontology
  • Cardiology
  • Public Health

Background:

  • Population aging is increasing global longevity.
  • Frailty syndrome is a growing concern in older adults.
  • Frailty and cardiovascular disease (CVD) are increasingly prevalent in aging populations.

Purpose of the Study:

  • To explore the relationship between frailty and CVD.
  • To identify shared risk factors and pathophysiological mechanisms.
  • To discuss the implications of inflammageing on both conditions.

Main Methods:

  • Review of original studies.
  • Comprehensive literature reviews.
  • Meta-analyses conducted by global researchers.

Main Results:

  • Frailty is overrepresented in individuals with CVD.
  • Frail individuals experience a greater burden of CVD.
  • Shared risk factors include hypertension, diabetes, and obesity.

Conclusions:

  • Inflammation and inflammageing are probable common pathophysiological drivers.
  • Understanding these links is crucial for managing aging populations.
  • Further research is needed to address the dual burden of frailty and CVD.

Keywords:
Cardiovascular diseaseEpidemiologyFrailtyRisk factors

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