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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
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In gastric emptying studies, a meal's liquid and...
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Assessment of the Gastrointestinal System I: Subjective Data01:17

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Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Anatomy of the Intestines01:23

Anatomy of the Intestines

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Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
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Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran
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OPTN/SRTR 2018 Annual Data Report: Intestine.

J M Smith1,2, T Weaver1, M A Skeans1

  • 1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|January 4, 2020
PubMed
Summary
This summary is machine-generated.

Intestine transplants remain crucial for intestinal failure, but patient and donor numbers have declined. Survival rates vary significantly by age and transplant type, with pediatric recipients showing better outcomes.

Keywords:
Intestinal failureintestine transplantintestine-liver transplantwaiting list

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Area of Science:

  • Transplantation Medicine
  • Gastroenterology
  • Surgical Innovation

Background:

  • Intestine transplantation is a vital treatment for intestinal failure.
  • Despite advances, organ availability and procedure numbers have decreased.
  • Graft failure rates have stabilized in recent years.

Purpose of the Study:

  • To analyze trends in intestine transplantation over the past decade.
  • To evaluate patient survival rates based on age and transplant type.
  • To highlight the current status and outcomes of intestine transplant procedures.

Main Methods:

  • Retrospective analysis of intestine transplant waiting list data.
  • Review of donor statistics and number of procedures performed.
  • Survival analysis stratified by patient age and transplant type (intestine vs. intestine-liver).

Main Results:

  • A significant decline in new patients added to the waiting list and available donors was observed by 2018.
  • The total number of intestine transplants performed reached a decade low in 2018, with 59% being combined intestine-liver transplants.
  • Patient survival rates varied, with 1- and 5-year survival at 66.7% and 49.1% for adult intestine-liver recipients, versus 89.1% and 76.4% for pediatric intestine recipients.

Conclusions:

  • Intestine transplantation continues to be an important therapeutic option for intestinal failure.
  • Declining donor and recipient numbers pose challenges to the field.
  • Pediatric intestine recipients demonstrate superior survival outcomes compared to adult combined intestine-liver recipients.