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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Prophylaxis measures for postinjection endophthalmitis.

Shriji N Patel1, Sapna Gangaputra1, Paul Sternberg1

  • 1Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Survey of Ophthalmology
|January 11, 2020
PubMed
Summary
This summary is machine-generated.

Intravitreal injections are common eye procedures. This review summarizes guidelines and literature on preventing postinjection endophthalmitis, a rare but serious complication.

Keywords:
anti-VEGFendophthalmitisintravitreal injectionpostinjectionpovidone-iodinesteroids

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Area of Science:

  • Ophthalmology
  • Retina Surgery
  • Infectious Disease

Background:

  • Intravitreal injections are the most frequent ophthalmic procedure, crucial for modern retina care.
  • Postinjection endophthalmitis is a rare but severe complication, necessitating robust preventive strategies.
  • Current protocols for preventing endophthalmitis vary significantly among specialists due to a lack of consensus.

Purpose of the Study:

  • To summarize consensus guidelines for intravitreal injection techniques.
  • To comprehensively review existing literature on preventing postinjection endophthalmitis.
  • To provide clarity on crucial prophylactic measures for retina specialists.

Main Methods:

  • Literature review of studies on endophthalmitis prevention after intravitreal injections.
  • Analysis of consensus guidelines for intravitreal injection procedures.
  • Collating data to identify risk factors for postinjection endophthalmitis.

Main Results:

  • Millions of intravitreal injections are performed annually, providing extensive data on risk factors.
  • Significant variation exists in prophylactic protocols despite proposed measures like antisepsis and sterile techniques.
  • Understanding risk factors is key to refining prevention strategies.

Conclusions:

  • Standardizing intravitreal injection techniques and prophylactic measures is essential.
  • Evidence-based guidelines can help reduce the incidence of postinjection endophthalmitis.
  • Further consensus among retina specialists may improve patient safety and outcomes.