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Updated: Dec 29, 2025

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
Published on: September 5, 2018
Lizard Brain: Tackling Locally Low-Dimensional Yet Globally Complex Organization of Multi-Dimensional Datasets
Jonathan Bac1,2,3,4, Andrei Zinovyev1,2,3,5
1Institut Curie, PSL Research University, Paris, France.
Abstract:
Machine learning deals with datasets characterized by high dimensionality. However, in many cases, the intrinsic dimensionality of the datasets is surprisingly low. For example, the dimensionality of a robot's perception space can be large and multi-modal but its variables can have more or less complex non-linear interdependencies. Thus multidimensional data point clouds can be effectively located in the vicinity of principal varieties possessing locally small dimensionality, but having a globally complicated organization which is sometimes difficult to represent with regular mathematical objects (such as manifolds). We review modern machine learning approaches for extracting low-dimensional geometries from multi-dimensional data and their applications in various scientific fields.
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