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Effect of reconstruction parameters on cone beam CT trabecular bone microstructure quantification in sheep
Aso Muhammad Ali Muhammad1, Norliza Ibrahim2, Rohana Ahmad3
1Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur, Malaysia.
BMC Oral Health
|February 12, 2020
Summary
Cone Beam Computed Tomography (CBCT) image reconstruction parameters affect trabecular bone assessment. While voxel size has minimal impact, reducing the threshold value by 15% significantly alters measurements, impacting bone microarchitecture analysis.
Area of Science:
- Radiology
- Biomedical Engineering
- Orthodontics
Background:
- Cone Beam Computed Tomography (CBCT) is a key imaging technique for evaluating bone structure.
- Assessing trabecular bone microarchitecture is crucial for various dental and orthopedic applications.
- Image reconstruction parameters can influence the accuracy of microarchitecture assessments.
Purpose of the Study:
- To investigate the impact of CBCT image reconstruction parameters on trabecular bone microstructure assessment.
- Specifically, to evaluate the effects of varying threshold values and reconstruction voxel sizes.
Main Methods:
- Sheep maxilla samples were scanned using CBCT at a 76 μm resolution.
- Images were reconstructed using different voxel sizes (76, 100, 200 μm³) and threshold adjustments (±15%).
- Trabecular bone parameters were analyzed using CTAn software.
Main Results:
- No significant differences in trabecular bone measurements were observed across different reconstruction voxel sizes.
- A significant difference in trabecular bone measurements was found when the global threshold value was decreased by 15% (p < 0.05).
- Specific parameters like Tb.N, Tb.Sp, Tb.Th, and BV/TV were significantly affected by threshold adjustments.
Conclusions:
- CBCT reconstruction voxel size does not compromise trabecular bone microstructure measurements.
- Applying a threshold value less than 15% below the global recommended value can significantly affect measurement accuracy.
- Careful selection of threshold values is essential for reliable CBCT-based bone microarchitecture analysis.
