Related Experiment Videos
[Prognostic factors and evolution in 92 children with acute lymphoblastic leukemia]
E Moya1, J L Bezanilla, A Navajas
1Departamento de Pediatria del Hospital de Cruces, Baracaldo, Vizcaya.
Anales Espanoles De Pediatria
|October 1, 1988
Summary
This study analyzed 92 pediatric patients with acute lymphoblastic leukemia (ALL), classifying them by risk factors to evaluate treatment outcomes. Findings help refine risk stratification for better ALL patient management.
Area of Science:
- Pediatric Oncology
- Hematology
- Clinical Research
Context:
- Acute lymphoblastic leukemia (ALL) is a common childhood cancer requiring precise risk stratification.
- Accurate prognostic factors are crucial for tailoring treatment intensity in pediatric ALL.
- Understanding treatment response across risk groups informs clinical decision-making.
Purpose:
- To analyze prognostic factors in 92 pediatric patients diagnosed with ALL.
- To classify patients into high, intermediate, and low-risk groups based on established factors.
- To evaluate treatment outcomes in relation to risk stratification and applied therapies.
Summary:
- Reviewed 92 pediatric ALL cases (age 1-12 years, 50 males, 42 females).
- Classified patients using prognostic factors: sex, age, visceromegaly, adenopathy, WBC, HB, immunoglobulins, platelets, FAB morphology, bone marrow response, immunological markers, CNS infiltration, and mediastinal mass.
- Analyzed individual factors and treatment results per risk group.
Impact:
- Provides insights into the efficacy of risk-based treatment strategies for pediatric ALL.
- Contributes to optimizing prognostic models for childhood ALL.
- Aids in developing more personalized treatment protocols for improved patient outcomes.