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Piroxicam.

Gamal A E Mostafa1, Abdullah S Al-Dosseri1, Abdullah A Al-Badr1

  • 1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Profiles of Drug Substances, Excipients, and Related Methodology
|March 14, 2020
PubMed
Summary
This summary is machine-generated.

This profile details piroxicam, covering its preparation, physical and chemical properties, and analytical methods. It also reviews stability, toxicity, pharmacokinetics, and bioavailability for comprehensive understanding.

Keywords:
Biological investigationsDescriptionMethods of analysisMethods of preparationPhysical characteristicsPiroxicamStabilityToxicity and reviews

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Area of Science:

  • Pharmaceutical Sciences
  • Medicinal Chemistry
  • Drug Analysis

Background:

  • Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) with established therapeutic uses.
  • A thorough understanding of its properties is crucial for quality control and therapeutic application.

Purpose of the Study:

  • To provide a comprehensive profile of piroxicam.
  • To detail its preparation, characterization, and analytical methodologies.
  • To review its stability, safety, and pharmacokinetic profile.

Main Methods:

  • Literature review of existing data on piroxicam.
  • Compilation of information on drug synthesis and characterization techniques.
  • Summary of analytical methods for bulk drug and formulations.
  • Review of stability, toxicity, and pharmacokinetic studies.

Main Results:

  • Detailed description of piroxicam's nomenclature, formula, elemental composition, and physical characteristics.
  • Outline of preparation methods and analytical techniques (compendial, spectrophotometric, electrochemical, chromatographic).
  • Inclusion of data on stability, toxicity, pharmacokinetics, and bioavailability.

Conclusions:

  • This profile serves as a valuable resource for researchers and professionals working with piroxicam.
  • It consolidates essential information for drug development, quality control, and clinical use.
  • Extensive referencing supports the compiled data.