RISK-FACTORS OF CORONARY ARTERY DISEASE (REVIEW)

M Kantaria1, M Buleishvili2, Nina V Kipiani3

  • 12Davit Aghmashenebeli University of Georgia; 3N. Kipshidze Central University Clinic; 4Georgian National University SEU, Tbilisi, Georgia.

Georgian Medical News
|April 4, 2020
PubMed

Insights

Effective coronary artery disease (CAD) treatment requires addressing risk factors alongside interventions like revascularization. Lifestyle changes and medication are crucial for long-term prevention of cardiovascular events.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Preventive Cardiology

Background:

  • Coronary artery disease (CAD) management often involves invasive procedures like percutaneous coronary intervention and coronary artery bypass grafting.
  • Revascularization alone does not fully protect against future thrombotic events in CAD patients.
  • Understanding the underlying causes of coronary artery conduction disturbances is key to improving treatment outcomes.

Purpose of the Study:

  • To discuss risk factors for developing coronary syndrome.
  • To explore strategies for improving treatment outcomes in patients with CAD.
  • To provide a new perspective on managing coronary artery disease.

Main Methods:

  • Review of existing literature on coronary artery disease treatment and prevention.
  • Analysis of risk factors contributing to coronary syndrome.
  • Examination of primary and secondary prevention trial data.

Main Results:

  • Management of modifiable risk factors (e.g., LDL-cholesterol, blood pressure, smoking) significantly reduces mortality and cardiovascular events.
  • Optimal treatment for CAD necessitates combining revascularization with long-term risk reduction strategies.
  • Updated guidelines incorporate modifiable, nonmodifiable, and emerging risk factors for atherosclerosis prevention.

Conclusions:

  • Successful CAD treatment hinges on a dual approach: effective revascularization and sustained risk factor modification.
  • Lifestyle changes and pharmacological interventions are essential for preventing recurrent cardiovascular events.
  • Comprehensive prevention strategies, considering all risk factors, are vital for managing atherosclerosis and CAD.

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