Micro-Raman spectroscopy as an enabling tool for long-term intracellular studies of nanomaterials at nanomolar concentration levels
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Updated: Dec 24, 2025
Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
Published on: May 29, 2012
T Ignatova1, S Chandrasekar, M Pirbhai
1Department of Materials Science and Engineering, Lehigh University, USA. ssj207@lehigh.edu rotkin@lehigh.edu.
Abstract:
Given the importance of nanomaterials for medicine, health and biological sciences, a method for reliable intra-cellular tracking of nanocarbon materials at ultra-low concentrations was investigated. Namely, hyperspectral imaging of DNA-functionalized single-walled carbon nanotubes inside neural stem cells was demonstrated, over several mitosis cycles, also in a 3D z-stacking mode.
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