[Indication of bloodletting therapy based on multi-dimensional evidence assessment]

Zhong-Xi Lv1, Yi-Nan Gong1, Yi Guo1

  • 1Institute of Acupuncture and Moxibustion Standardization, Tianjin University of TCM, Tianjin 300193, China.

Insights

This study determined evidence-based indications for bloodletting therapy, identifying key conditions like herpes zoster and stroke. These findings offer guidance for the safe and effective clinical use of bloodletting.

Area of Science:

  • Integrative Medicine
  • Traditional Chinese Medicine (TCM) Evidence Assessment
  • Clinical Practice Guidelines

Background:

  • Bloodletting therapy, a historical medical practice, requires updated clinical guidelines.
  • Assessing the evidence base for traditional therapies is crucial for modern medical integration.

Purpose of the Study:

  • To establish evidence-based indications for bloodletting therapy.
  • To provide guidance for the clinical application of bloodletting in contemporary practice.

Main Methods:

  • Comprehensive literature retrieval from major Chinese databases (CNKI, Wanfang, VIP) and traditional texts.
  • Disease spectrum determination via expert questionnaire survey.
  • Indication finalization through a Delphi expert meeting and multi-dimensional evidence assessment.

Main Results:

  • Inclusion of 746 ancient and 32,775 modern literature sources.
  • Identified indications include herpes zoster, acne, acute tonsillitis, vascular headache, varicose veins, acute lumbar sprain, erysipelas, wheat swelling, pediatric exogenous fever, and stroke.
  • Predominant syndromes treated are blood stasis, toxin, excess, and heat.

Conclusions:

  • Multi-dimensional evidence assessment provides a robust framework for determining bloodletting therapy indications.
  • Established indications offer a foundation for standardized and evidence-informed application of bloodletting therapy.
  • The identified indications align with TCM syndromes of blood stasis, toxin, excess, and heat.

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