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Published on: November 20, 2016
[Indication of bloodletting therapy based on multi-dimensional evidence assessment]
Zhong-Xi Lv1, Yi-Nan Gong1, Yi Guo1
1Institute of Acupuncture and Moxibustion Standardization, Tianjin University of TCM, Tianjin 300193, China.
Insights
This study determined evidence-based indications for bloodletting therapy, identifying key conditions like herpes zoster and stroke. These findings offer guidance for the safe and effective clinical use of bloodletting.
Area of Science:
- Integrative Medicine
- Traditional Chinese Medicine (TCM) Evidence Assessment
- Clinical Practice Guidelines
Background:
- Bloodletting therapy, a historical medical practice, requires updated clinical guidelines.
- Assessing the evidence base for traditional therapies is crucial for modern medical integration.
Purpose of the Study:
- To establish evidence-based indications for bloodletting therapy.
- To provide guidance for the clinical application of bloodletting in contemporary practice.
Main Methods:
- Comprehensive literature retrieval from major Chinese databases (CNKI, Wanfang, VIP) and traditional texts.
- Disease spectrum determination via expert questionnaire survey.
- Indication finalization through a Delphi expert meeting and multi-dimensional evidence assessment.
Main Results:
- Inclusion of 746 ancient and 32,775 modern literature sources.
- Identified indications include herpes zoster, acne, acute tonsillitis, vascular headache, varicose veins, acute lumbar sprain, erysipelas, wheat swelling, pediatric exogenous fever, and stroke.
- Predominant syndromes treated are blood stasis, toxin, excess, and heat.
Conclusions:
- Multi-dimensional evidence assessment provides a robust framework for determining bloodletting therapy indications.
- Established indications offer a foundation for standardized and evidence-informed application of bloodletting therapy.
- The identified indications align with TCM syndromes of blood stasis, toxin, excess, and heat.
Abstract:
The indication of bloodletting therapy was determined based on the multi-dimensional evidence assessment, which could provide guidance for the clinical application of bloodletting therapy. The literature of bloodletting therapy was comprehensively collected by retrieval in CNKI, Wanfang and VIP databases (until February 23, 2019), modern books in Library of Tianjing University of TCM and the Chinese Medical Code (Fifth Edition). The disease spectrum of bloodletting therapy was determined by self-designed questionnaire survey e-mailed to relevant experts. The indication of bloodletting therapy was determined by Delphi expert meeting. As a result, 746 pieces of ancient literature and 32 775 modern literature were included. The indications of bloodletting therapy based on the multi-dimensional evidence assessment include herpes zoster, acne, acute tonsillitis, vascular headache, varicose veins of lower extremities, acute lumbar sprain, early erysipelas, wheat swelling, exogenous fever of children, stroke, which are mainly the syndromes of blood stasis, toxin, excess and heat.
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