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Updated: Dec 23, 2025

Coherent Anti-Stokes Raman Spectroscopy CARS Application for Imaging Myelination in Brain Slices
Published on: July 22, 2022
Raman spectroscopy and neuroscience: from fundamental understanding to disease diagnostics and imaging
Taylor D Payne1, Amber S Moody2, Avery L Wood1
1University of Tennessee, Knoxville, 1420 Circle Drive, Knoxville, TN 37996, USA. bhavya.sharma@utk.edu.
Abstract:
Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years.
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