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Updated: Dec 23, 2025

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice
Published on: November 29, 2013
Effects of Exercise on Long-Term Potentiation in Neuropsychiatric Disorders
1Department of Health, Exercise Science, and Recreation Management, Exercise and Memory Laboratory, The University of Mississippi, Oxford, MS, USA. pdloprin@olemiss.edu.
Abstract:
Various neuropsychiatric conditions, such as depression, Alzheimer's disease, and Parkinson's disease, demonstrate evidence of impaired long-term potentiation, a cellular correlate of episodic memory function. This chapter discusses the mechanistic effects of these neuropsychiatric conditions on long-term potentiation and how exercise may help to attenuate these detrimental effects.
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