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Evaluation of the Differences Between Measurements in Multiple Institutions and Calculation Modeled by Representative
Hironao Goto1, Hirokazu Mizuno2, Yuichi Akino3
1Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Osaka, Japan.
In Vivo (Athens, Greece)
|May 2, 2020
Summary
This study found good agreement between patient-specific quality assurance measurements and treatment planning system calculations for radiation therapy. Standardizing multi-leaf collimator parameters across institutions can enhance consistency in treatment delivery.
Area of Science:
- Medical Physics
- Radiation Oncology
- Radiotherapy Quality Assurance
Background:
- Patient-specific quality assurance (QA) is crucial for verifying radiotherapy accuracy.
- Discrepancies may arise between institutional measurements and treatment planning system (TPS) calculations, particularly concerning multi-leaf collimator (MLC) parameters.
Purpose of the Study:
- To investigate potential differences between multi-institutional measurements and TPS calculations for patient-specific QA.
- To assess the impact of MLC parameters on radiotherapy accuracy across different institutions.
Main Methods:
- Eleven TrueBeam linear accelerators from nine institutions were utilized.
- Volumetric Arc Therapy (VMAT) plans were created using the Eclipse TPS.
- Point dose measurements (CC13 ionization chamber) and dose distribution analysis (GAFCHROMIC EBT3 film) were performed.
Main Results:
- Point dose differences in patient-specific QA averaged 1.0% ± 0.6%.
- Mean gamma pass rates for dose distribution exceeded 99% for 3%/2 mm and 96% for 2%/2 mm criteria.
Conclusions:
- Good agreement was observed between measured and calculated dose distributions.
- Complex VMAT had minimal influence on underlying radiotherapy processes.
- Standardizing MLC parameters within TPS across institutions with similar planning policies is recommended for consistency and efficiency.
