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Area of Science:

  • Global Health
  • Infectious Diseases
  • Cardiology

Background:

  • Chagas disease (CD) is a neglected tropical disease caused by *Trypanosoma cruzi*, primarily affecting the cardiovascular system.
  • It is a chronic, stigmatizing condition linked to poverty, impacting millions globally with a growing international presence.
  • Characterized by a long asymptomatic phase, approximately 30% of infected individuals develop severe cardiac complications, including heart failure and stroke.

Purpose of the Study:

  • To develop a comprehensive roadmap for the prevention, diagnosis, and management of Chagas disease.
  • To identify and analyze obstacles hindering access to comprehensive care for Chagas disease patients.
  • To propose evidence-based strategies and solutions for healthcare professionals, authorities, and governments to address these barriers.

Main Methods:

  • Convened a diverse group of 20 Chagas disease experts from the World Heart Federation (WHF) and Inter-American Society of Cardiology (IASC).
  • Conducted an extensive literature review on obstacles and solutions for CD diagnosis and treatment.
  • Utilized a survey distributed to WHF Members and healthcare professionals, supplemented by snowball sampling, to gather broader community input.

Main Results:

  • The WHF IASC Roadmap provides a comprehensive overview of current knowledge on Chagas disease prevention, diagnosis, and management.
  • Analysis of 'roadblocks' in patient care access was conducted, considering healthcare system capabilities, governance, financing, community awareness, and advocacy.
  • Consolidated findings from expert knowledge, literature review, and community surveys formed the basis of the roadmap.

Conclusions:

  • The roadmap offers actionable strategies and evidence-based solutions to overcome barriers in comprehensive Chagas disease care.
  • It outlines an ideal patient care pathway, highlighting challenges and proposing practical solutions.
  • The document serves as a call to action for decision-makers and healthcare professionals to intensify efforts towards Chagas disease eradication.