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Plasma 10-hydroxynortriptyline and therapeutic response in geriatric depression
R C Young1, G S Alexopoulos, R Shindledecker
1Department of Psychiatry, New York Hospital-Cornell Medical Center, NY.
Abstract:
Geriatric inpatients with major depression received nortriptyline for 4 weeks. Plasma E-10-hydroxynortriptyline concentrations were correlated positively with residual Hamilton depression ratings and negatively with changes in ratings.