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Updated: Dec 18, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
Focus on the 2019 novel coronavirus (SARS-CoV-2)
1National Center for Birth Defect Monitoring, Key Laboratory of Birth Defects & Related Diseases of Women & Children, Ministry of Education, West China Second University Hospital, & State Key Laboratory of Biotherapy, Sichuan University, Chengdu, PR China.
Abstract:
A new coronavirus, severe acute respiratory syndrome coronavirus 2, was first discovered in Wuhan, China, in December 2019. As of 7 April 2020, the new coronavirus has spread quickly to 184 countries and aroused the attention of the entire world. No targeted drugs have yet been available for intervention and treatment of this virus. The sharing of academic information is crucial to risk assessment and control activities in outbreak countries. In this review, we summarize the epidemiological, genetic and clinical characteristics of the virus as well as laboratory testing and treatments to understand the nature of the virus. We hope this review will be helpful to prevent viral infections in outbreak countries and regions.
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