THE DESIGN OF THE ARTERIOVENOUS VASCULAR LOOP DOES NOT AFFECT ITS PATENCY: EXPERIMENTAL STUDY

Area of Science:

• Vascular surgery
• Microsurgery
• Animal models

Background:

• Vascular loops are crucial for creating arteriovenous access.
• Optimizing vascular loop design is essential for ensuring patency and minimizing complications.
• Rabbit femoral artery models offer a platform for evaluating surgical techniques.

Purpose of the Study:

• To assess the impact of femoral vascular loop design (circular vs. angled) on patency.
• To compare the efficacy of two distinct vascular loop configurations in a rabbit model.
• To evaluate hemodynamic changes and hemolysis associated with different loop designs.

Main Methods:

• Microsurgical arteriovenous microanastomosis was performed on 39 rabbits.
• Two vascular loop designs, circular and angled, were implemented.
• Patency, hemolysis, and hemodynamic parameters were assessed after seven days.

Main Results:

• No significant difference in patency was observed between angled (68%) and circular (75%) loops after seven days (p > 0.05).
• Intragroup analysis revealed a significant decrease in partial pressure of carbon dioxide (pCO2) and an increase in pH.
• No significant differences were found in other evaluated parameters between the two loop models.

Conclusions:

• A reproducible vascular loop model in rabbits was established.
• Both circular and angled femoral vascular loop designs demonstrated comparable patency rates after seven days.
• The study suggests that loop design has no significant impact on short-term patency in this model.