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Updated: Dec 17, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Imaging for Metastatic Renal Cell Carcinoma.
Soumya V L Vig1, Elcin Zan1, Stella K Kang2
1Department of Radiology, NYU Langone Medical Center, New York, NY 10016, USA.
Monitoring for recurrent renal cell carcinoma (RCC) after surgery is crucial. Advanced imaging techniques, including CT/MRI and nuclear medicine, help detect metastases and assess treatment response in patients with this cancer.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Renal cell carcinoma (RCC) recurrence and metastasis post-nephrectomy necessitate vigilant surveillance.
- Current imaging protocols are tailored to suspected sites of disease spread.
Purpose of the Study:
- To outline the critical role of imaging in monitoring for recurrent or metastatic renal cell carcinoma (RCC) after radical nephrectomy.
- To discuss the evolution of radiologic reporting and the integration of novel nuclear medicine agents in RCC management.
Main Methods:
- Computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen and pelvis are primary diagnostic tools.
- Specialized imaging (e.g., bone scans, MRI of the brain) is employed for symptomatic patients.
- Nuclear medicine studies are being evaluated for enhanced tumor staging and treatment response assessment.
Main Results:
- Imaging plays a pivotal role in detecting disease recurrence and metastases following RCC surgery.
- Radiologic reporting is adapting to incorporate the impact of systemic therapies on lesion appearance.
- Emerging nuclear medicine agents show promise for improved staging accuracy in metastatic RCC.
Conclusions:
- Effective imaging strategies are essential for timely detection of recurrent or metastatic renal cell carcinoma.
- Continued research in imaging modalities and reporting standards is vital for optimizing patient care and treatment selection in metastatic RCC.
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