Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

423
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
423
Stress and Mental Health01:30

Stress and Mental Health

399
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
399
Psychological Responses to Stress01:20

Psychological Responses to Stress

403
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
403
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

337
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
337
Types of Stressors01:23

Types of Stressors

528
A stressor is any event, condition, or stimulus that triggers stress and causes a physical or psychological response in the body. Stressors can be categorized into three main types: catastrophes; significant life changes; and daily hassles, including social stress. Each can be detrimental to physical and mental well-being.
Catastrophes
Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...
528
Dissociative Disorders01:27

Dissociative Disorders

320
Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...
320

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Vestibular cortex and vestibular agnosia].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Headache in cerebrovascular diseases].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Central sensitization in patients with cerebral small vessel disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Epidemiology and some clinical aspects of primary headaches in children and adolescents].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025
Same author

[Alexithymia - traditional and advanced studies].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025
Same author

[Chronic traumatic encephalopathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025
Same journal

[The role of the cerebellum in the coordination of brain activity and the development of autism spectrum disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[A clinical case of anxiety-hypochondriacal depression with extensive somatized symptoms in the elderly].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[De novo variant in the ATP2B2 gene as a cause of neuropsychiatric developmental disorder].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Electroencephalographic predictors of olfactory stimulus discrimination in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Effect of long-term carbamazepine therapy on bone metabolism in women with epilepsy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Glial-derived neurotrophic factor and neuropsychological status in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
See all related articles

Related Experiment Video

Updated: Dec 16, 2025

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
05:28

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

23.2K

[Stress-induced disorders].

R G Esin1,2, O R Esin2, A R Khakimova1

  • 1Kazan State Medical Academy, Kazan, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|July 5, 2020
PubMed
Summary
This summary is machine-generated.

This review examines stress-related diseases, highlighting the role of gamma-aminobutyric acid (GABA) in mitigating stress effects. Aminophenylbutyric acid hydrochloride is recommended for its protective benefits against stress-induced damage.

Keywords:
aminophenylbutyric acid hydrochlorideanvifenstressstressors

More Related Videos

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

749
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

18.3K

Related Experiment Videos

Last Updated: Dec 16, 2025

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
05:28

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

23.2K
Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

749
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

18.3K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Pharmacology

Background:

  • Acute and chronic stress significantly impact health, leading to various diseases.
  • Stress pathogenesis involves an imbalance between sympathetic and parasympathetic nervous systems.
  • Numerous organ systems, including cardiovascular, respiratory, immune, skin, and gastrointestinal, are affected by stress.

Purpose of the Study:

  • To analyze diseases and conditions resulting from acute and chronic stress.
  • To elucidate the pathogenesis of stress-induced disorders.
  • To identify protective agents against stress-related damage.

Main Methods:

  • Review of existing literature on stress and its physiological effects.
  • Analysis of the role of the sympathetic and parasympathetic nervous systems in stress response.
  • Examination of the neurochemical mechanisms involved in stress adaptation.

Main Results:

  • Stress significantly impacts cardiovascular, respiratory, immune, skin, and gastrointestinal systems.
  • Gamma-aminobutyric acid (GABA) is identified as a key mediator in stress limitation.
  • GABA protects the nervous system and target organs from stress-induced damage.

Conclusions:

  • Imbalance in stress systems contributes to various stress-related disorders.
  • Aminophenylbutyric acid hydrochloride, a GABA analogue, demonstrates protective effects.
  • Aminophenylbutyric acid hydrochloride is a well-tolerated option for mitigating stress impacts in adults and children.